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Family Practice Vol. 16, No. 3, 269-277
© Oxford University Press 1999

Evidence-based guidelines for the management of genital chlamydial infection in general practice

Tim Stokes, Paul Schobera, Janet Bakerb, Anita Bloorc, Isabel Kuncewiczd, Jenny Ogilvye, Adrian Frenchf, Carol Henrye, Judith Mearsc and (leicestershire Chlamydia Guidelines Group)

Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW,
a Department of Genito-Urinary Medicine, The Leicester Royal Infirmary NHS Trust, Leicester LE1 5WW,
b The Surgery, Whitwick Road, Coalville LE67 3FA,
c Uppingham Road Health Centre, 131 Uppingham Road, Leicester LE5 4BP,
d The Central Surgery, Brooksby Drive, Oadby LE2 5AA,
e Bridge Street Medical Practice, 20 Bridge Street, Loughborough LE11 1NQ,
f General Practice Postgraduate Education Department, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK.

Dr TN Stokes, Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK.

Background. Valid clinical guidelines can be effective in improving patient care. Genital Chlamydia trachomatis infection is the commonest curable sexually transmitted disease (STD) in England and Wales and is an important cause of pelvic inflammatory disease (PID), tubal infertility and ectopic pregnancy. No published guidelines exist on managing genital chlamydial infection in British general practice.

Objective. We aimed to develop valid guidelines for the management of genital chlamydial infection for use in British general practice.

Methods. A district-wide postal questionnaire survey was used to document current clinical practice. A critical review of the evidence concerning the management of genital chlamydial infection as it relates to British general practice was performed. The information gained from the critical review and survey was used to develop evidence-based guidelines within a multidisciplinary guideline recommendation group.

Results. The guidelines covered the diagnosis, investigation, drug treatment and referral of adult male and female patients with genital chlamydial infection in general practice.

Conclusion. Valid guidelines for the management of genital chlamydial infection have been developed for use in British general practice. Appropriate dissemination and implementation of the guidelines should lead to earlier detection and treatment of men and women with chlamydial infection and thereby reduce the incidence of PID, tubal infertility and ectopic pregnancy in women.

Keywords. Chlamydia trachomatis, general practice, guidelines.


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